![]() In the LDB, mTBI mice spent significantly less time on the far side of the arena than control mice. During the 30-min test period of the MBT, mTBI mice buried significantly more marbles than control mice. ![]() In the EPM and OF tests, there were no significant differences between the groups. Seven days post-injury, mice were subjected to one of five different behavioral tests: Elevated Plus Maze (EPM), Open Field apparatus (OF), Marble Burying test (MBT), Light Dark Box (LDB), and the Light Spot test within the PhenoTyper home cage (LS). ICR mice underwent mTBI using the weight-drop model. This study aims to evaluate behavioral tests designed to assess anxiety-like phenotypes in a mice model of mTBI. Anxiety is the most common complaint after mTBI in humans. Mild TBI (mTBI) accounts for the majority of TBI cases. Traumatic brain injury (TBI) is a primary global health concern and one of the most common causes of neurological impairments in people under 50. 8School of Behavioral Sciences, Netanya Academic College, Netanya, Israel.7Myers Neuro-Behavioral Core Facility, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. ![]() Adelson Chair and Center for the Biology of Addictive Diseases, Tel-Aviv University, Tel-Aviv, Israel 5Sylvan Adams Sports Institute, Tel Aviv University, Tel Aviv, Israel.4Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel.Adelson Clinic for Drug Abuse Treatment and Research, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel 2Department of Psychiatry, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.1Department of Anatomy and Anthropology, Tel Aviv University Sackler Faculty of Medicine, Tel Aviv, Israel.Liron Tseitlin 1, Bar Richmond-Hacham 1, Adi Vita 1, Shaul Schreiber 2,3,4, Chaim G.
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